Compile Data Set for Download or QSAR
Found 146 of ic50 data for polymerid = 50000136,50001742,50002606
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50471296(CHEMBL87935)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9MPZPubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290686(9-((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44FK
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50290686(9-((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50471292(CHEMBL315230)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9MPZPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50471294(CHEMBL276855)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9MPZPubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217841(REVEROMYCIN A)copy SMILEScopy InChI
Affinity DataIC50: 1.97nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50471297(CHEMBL424608)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9MPZPubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093001((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-3-methyl-butyryl...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50471293(CHEMBL83449)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9MPZPubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093003((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50470911(CHEMBL122825)copy SMILEScopy InChI
Affinity DataIC50: 4.45nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3J3GPubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217841(REVEROMYCIN A)copy SMILEScopy InChI
Affinity DataIC50: 4.46nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1G6FPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50471295(CHEMBL312853)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition concentration against Isoleucyl-tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9MPZPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50471291(CHEMBL83394)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition concentration against isoleucyl tRNA synthetase from Staphylococcus aureus NCTC 6571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9MPZPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50470914(CHEMBL120343)copy SMILEScopy InChI
Affinity DataIC50: 6.67nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureus NCTC 3571More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3J3GPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50470913(CHEMBL120798)copy SMILEScopy InChI
Affinity DataIC50: 6.87nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3J3GPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50470912(CHEMBL120437)copy SMILEScopy InChI
Affinity DataIC50: 7.98nMAssay Description:Inhibitory activity against isoleucyl-tRNA synthetase (IRS) of Staphylococcus aureusMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3J3GPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50093003((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366870(CHEMBL605376)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BRSPubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093004((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479281(2,3-DIHYDROREVEROMYCIN A)copy SMILEScopy InChI
Affinity DataIC50: 17.5nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1G6FPubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075061(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479274(4-HYDROXY REVEROMYCIN A)copy SMILEScopy InChI
Affinity DataIC50: 21.7nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1G6FPubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093002((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075059(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Compound tested for the inhibition of human isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479284(CHEMBL442945)copy SMILEScopy InChI
Affinity DataIC50: 36.9nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1G6FPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50093001((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-3-methyl-butyryl...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366862(CHEMBL605592)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BRSPubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50075056(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217935(CHEMBL114859)copy SMILEScopy InChI
Affinity DataIC50: 44.4nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075070(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Compound tested for the inhibition of human Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50075058(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50075067(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50093004((4aR,6S,7R,7aS)-7-[2-((2S,3S)-2-Amino-3-methyl-pen...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from staphylococcus aureus WCUH29More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50093005((4aR,6S,7R,7aS)-7-[2-((S)-2-Amino-4-methyl-pentano...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Compound was evaluated for its inhibitory activity against Isoleucyl-tRNA synthetase from rat liverMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PN94W3PubMed
TargetIsoleucyl-tRNA synthetase(Rattus norvegicus)
RIKEN (The Institute of Physical and Chemical Research)

Curated by ChEMBL
LigandPNGBDBM50217844(CHEMBL115953)copy SMILEScopy InChI
Affinity DataIC50: 74.4nMAssay Description:Inhibitory concentration against Isoleucyl-tRNA synthetase (IleRS) activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B56MX8PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50479277(2,3-DIHYDRO-5-EPIREVEROMYCIN A)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1G6FPubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50075069(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50222902(CHEMBL1163069)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibitory activity against Escherichia coli Isoleucyl-tRNA synthetase was determinedMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BRSPubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075068(((2S,3S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of S. aureus isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase(Staphylococcus aureus)
SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL
LigandPNGBDBM50075055(((S)-2-Amino-4-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound tested for the inhibition of S. aureus Leucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075063(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290689(9-{(E)-4-[(2S,3R,4R,5S)-5-(3-Chloro-propane-1-sulf...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Compound was evaluated for inhibitory activity against Isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z44FK
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50217935(CHEMBL114859)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of IleRSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BK1G6FPubMed
TargetIsoleucine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50075065(((S)-2-Amino-3-methyl-pentanoyl)-sulfamic acid (2R...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of E. coli isoleucyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M32TX1PubMed
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